Medical Use of Kanna

Posted by on Jan 12, 2014 | 2 comments

What is it?

By isolating this and other bio-chemically active compounds, researchers are now confirming what many people have known for many hundreds of years: that Sceletium has a remarkable ability to effectively treat symptoms of anxiety.

Mesembrine is an alkaloid which is derived from the Sceletium Tortuosum plant and is now being acknowledged as a key active component in the ability of the plant to produce beneficial effects (closely related to it are the alkaloids mesembrenone, mesembrenol and tortuosamine, which are also present and produce very similar effects to mesembrine).

It is a confirmed serotonin (re)-uptake inhibitor – as understood by the US Patent office – which means that it regulates the effects of one of the brain’s most important neurotransmitters.

What are its benefits?

Individuals suffering from depression and anxiety can benefit greatly from this substance.

Mesembrine works in the following manner: the brain is made up of countless neurons, which transmit signals to each other only by jumping the “gap” (synapse) to neighboring neurons. However, the signal cannot jump the synapse without assistance.

The message can only travel when the neuron releases a neurotransmitter to fill this gap and allow the signal to transient via it.

The receiving neuron has many points on its surface that which act as potential locks, each of which is known as a receptor and is effected by a particular type of neurotransmitter. When sufficient amounts of the neurotransmitter are received by the relevant receptor, a nerve impulse is started and the message continues to its ultimate destination. To permit recovery of the neuron to receive new messages, the brain takes away the neurotransmitter from the neuron receptors and permitting it to be sent back to the originating nerves, a process known as re-uptake.

In individuals suffering from depression, the neurotransmitter serotonin (also known as 5-hydroxytryptamine) is lacking. Mesembrine slows down the re-uptake process, making it more probable there will be more serotonin in the relevant receptors, greatly increasing the possibility that there will be sufficient levels to set up the signal transfer in all neighboring neurons.

Mesembrine allows the brain to function with reduced levels of serotonin, allowing time for natural levels to build up, whereupon the mesembrine dosage can be reduced or eliminated.

Are there any side effects?

Mesembrine will not produce any major side effects, but some individuals will experience drowsiness, thus it must not be taken before operating any type of machinery or. Also, it should not be taken in conjunction with any other psychoactive substance or by pregnant or nursing women, except under the supervision of your health professional.


  1. Hi, I need some advice. I need a mood elevator and something to curve bouts of anxiety. I’ve been dealing with this battle for about six years. I’m sick of booze because it makes me tired and Xanax although I can get it is like a Band-Aid and a poor one at that. I’m a healthy person and I force myself to eat right and exercise daily but evenings and mornings are a complete bear and I really need some help. I don’t trust the psychiatric community although I am well insured because all they want to do is load me up on prescription drugs that freak me out. I’ve been reading about canna and I think I want to try it. Will you please get back to me as soon as possible and I will make the appropriate purchase. Thanks enough a lot guys. Peace, Ted

    • Ted,

      We recommend taking a look at the popular Kanna products over at ShamansGarden: Kanna at Shaman’s Garden


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